I am using the Handy Pulse Laser for breaking down the calcification of Dupuytren's. The laser is definitely helping to keep my hand more supple and the lump and tightness have softened considerably. It is not a one hit wonder and I need to use it regularly to get the problem to diminish. I also have osteoarthritis in my lower back. It is harder to use because I cannot see and have to go by where it's sore. I need to be more consistent in using the laser on this problem.